Our Science

Scientific Conference Presentations – 2017

Posters and presentations presented at ASM Microbe, New Orleans, June 2017:

Poster Title:  Reversibility of b-lactamase inhibition by the broad-spectrum diazabicyclooctenone serine b-lactamase inhibitor ETX2514
Presented by:  Adam Shapiro
Meeting:  ASM Microbe, New Orleans, June 2017

Poster Title:  Cefpodoxime proxetil/ETX0282: A novel oral β-lactam/β-lactamase inhibitor combination to treat the emerging threat of multi-drug resistant Enterobacteriaceae
Presented by:  John O’Donnell
Meeting:  ASM Microbe, New Orleans, June 2017

Poster Title:  The Antibacterial Activity of Sulbactam and the Novel b-lactamase Inhibitor ETX2514 Combined with Imipenem or Meropenem Against Recent Clinical Isolates of Acinetobacter baumannii and Pseudomonas aeruginosa
Presented by:  Sarah McLeod
Meeting:  ASM Microbe, New Orleans, June 2017

Poster Title:  The Antibacterial Activity of Cefpodoxime and the Novel b-lactamase Inhibitor ETX1317 Against Recent Clinical Isolates of b-lactamase-producing Enterobacteriaceae
Presented by:  Sarah McLeod
Meeting:  ASM Microbe, New Orleans, June 2017

Presentation Title:  ETX0282, a Novel Oral Agent Against Multidrug-Resistant Enterobacteriaceae
Presented by:  Thomas Durand-Reville
Meeting:  ASM Microbe, New Orleans, June 2017

Presentations presented at ECCMID, Vienna, April 2017:

Presentation Title:  ETX2514: Responding to the global threat of nosocomial multidrug and extremely drug resistant Gram-negative pathogens
Presented by:  Ruben Tommasi
Meeting:  ECCMID, Vienna, April 2017

Presentation Title:  ETX2514 restoration of sulbactam activity against multidrug resistant Acinetobacter baumannii correlates with β-lactamase inhibition in vitro and in vivo
Presented by:  Alita Miller
Meeting:  ECCMID, Vienna, April 2017

Presentations presented at 2017 Pew-NIAID Workshop, Washington, DC, February 2017

Presentation Title: Improving our understanding of porin permeability in Gram-negative bacteria
Presented by: Ruben Tommasi
Meeting: Pew-NIAID Workshop, 2017

Presentations presented at 2017 Gordon Research Conference:  Multi-Drug Efflux Systems, Galveston, TX, March 2017:

Presentation Title: Antibiotic Resistance:  A real and present danger in our hospitals
Presented by: Ruben Tommasi
Meeting: Gordon Research Conference: Multi-Drug Efflux Systems, 2017

Presentations presented at 2017 ACS Meeting, San Francisco, CA, April 2017:

Presentation Title: Discovery of ETX2514, a novel, rationally designed inhibitor of Class A, C and D B-lactamases, for the treatment of Gram-negative infections
Presented by: Thomas Durand-Reville
Meeting: ACS Meeting, 2017

Presentations presented at SDRI, Brisbane, Australia, April 2017:

Presentation Title: Pathogen-directed strategies at Entasis Therapeutics
Presented by: Alita Miller
Meeting: SDRI, 2017

“Our scientific approach and expertise, coupled with Entasis’ strong pipeline of programs, really make us stand out in the field of antibacterial drug discovery and development.”

— Satenig Guler, Senior Scientist