Our Science

Publications 2016

Our scientific publications in high-quality journals reflect the quality of the innovative research in Entasis’ laboratories.

Papp JR,  Lawrence K, Sharpe S, Mueller J, Kirkcaldy  R
In vitro growth of multidrug-resistant Neisseria gonorrhoeae isolates is inhibited by ETX0914, a novel spiropyrimidinetrione
International Journal of Antimicrobial Agents (2016)

Shapiro, A
Investigation of β-lactam antibacterial drugs, β-lactamases, and penicillin-binding proteins with fluorescence polarization and anisotropy: a review
Methods and Applications in Fluorescence (2016)

Miller, A
Antibacterial Development: a Changing Landscape
Microbe (2016)

Giacobbe R, Huband M, deJonge B, Bradford P
Effect of Susceptibility Testing Conditions on the In Vitro Antibacterial Activity of ETX0914
Diagnostic Microbiology and Infectious Disease (2016)

Guo J, Joubran C, Luzietti RA Jr, Basarab GS, Grimm SW, Vishwanathan K
Absorption, distribution, metabolism and elimination of 14C-ETX0914, a novel inhibitor of bacterial type-II topoisomerases in rodents
Xenobiotica (2016)

“Our scientific approach and expertise, coupled with Entasis’ strong pipeline of programs, really make us stand out in the field of antibacterial drug discovery and development.”

— Satenig Guler, Senior Scientist